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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BIRC3 All Species: 12.73
Human Site: S109 Identified Species: 25.45
UniProt: Q13489 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13489 NP_001156.1 604 68372 S109 V N N L E A T S Q P T F P S S
Chimpanzee Pan troglodytes XP_508719 604 68367 S109 V N N L E A T S Q P T F P S S
Rhesus Macaque Macaca mulatta XP_001095970 604 68451 S109 V N N S E A T S Q P A F P S S
Dog Lupus familis XP_538165 615 69039 E140 A G I N K D E E F V E E F N R
Cat Felis silvestris
Mouse Mus musculus O08863 600 67180 P107 A N S L E A S P R P S L P S T
Rat Rattus norvegicus Q9R0I6 496 56054 T32 E E F N R L K T F A N F P S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509526 607 68021 A112 P G A S S Y S A F C P P P L G
Chicken Gallus gallus Q90660 611 68991 P116 S T H S A F S P L V A S N L S
Frog Xenopus laevis A5D8Q0 488 55110 S24 Q C P K M S D S A C D V D T D
Zebra Danio Brachydanio rerio NP_919376 628 70080 S109 T A N L L S S S H S A F S P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24307 498 54520 G34 A E D L V A N G F F A T G N W
Honey Bee Apis mellifera XP_396819 518 59795 G54 K I S D W N Y G D Q A I V R H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.6 20.6 N.A. 74 33.4 N.A. 73.4 67.4 32.7 54.2 N.A. 30.7 32.4 N.A. N.A.
Protein Similarity: 100 99.3 98 37.2 N.A. 85.4 48 N.A. 84.6 79.7 50.1 68.9 N.A. 48.6 51.8 N.A. N.A.
P-Site Identity: 100 100 86.6 0 N.A. 46.6 26.6 N.A. 6.6 6.6 6.6 26.6 N.A. 13.3 0 N.A. N.A.
P-Site Similarity: 100 100 86.6 13.3 N.A. 80 33.3 N.A. 20 20 20 40 N.A. 26.6 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 9 9 0 9 42 0 9 9 9 42 0 0 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 17 0 0 0 0 0 % C
% Asp: 0 0 9 9 0 9 9 0 9 0 9 0 9 0 9 % D
% Glu: 9 17 0 0 34 0 9 9 0 0 9 9 0 0 0 % E
% Phe: 0 0 9 0 0 9 0 0 34 9 0 42 9 0 0 % F
% Gly: 0 17 0 0 0 0 0 17 0 0 0 0 9 0 9 % G
% His: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 9 % H
% Ile: 0 9 9 0 0 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 9 0 0 9 9 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 42 9 9 0 0 9 0 0 9 0 17 9 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 34 34 17 0 9 9 0 0 0 9 0 9 17 0 % N
% Pro: 9 0 9 0 0 0 0 17 0 34 9 9 50 9 0 % P
% Gln: 9 0 0 0 0 0 0 0 25 9 0 0 0 0 0 % Q
% Arg: 0 0 0 0 9 0 0 0 9 0 0 0 0 9 9 % R
% Ser: 9 0 17 25 9 17 34 42 0 9 9 9 9 42 42 % S
% Thr: 9 9 0 0 0 0 25 9 0 0 17 9 0 9 9 % T
% Val: 25 0 0 0 9 0 0 0 0 17 0 9 9 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _